I think anything over 17-18PSI with the 20g and stock injectors gets scary. I was running in the 130% duty cycle range with that setup. Alcohol injection really helped, especially injecting Methanol. There were points, however, where I was still hitting 13.0AFR's with 55PSI of fuel pressure. This summer I decided to stop playing so close to the edge and put in a set of 36# injectors I bought off the Buick board for a very low price. I now have plenty of fuel at only 38-40lb of fuel pressure with the Methanol.
If you have a wideband or know someone who has one it will tell you on your truck where you are at. It seems to be the general theory lately that it is better to put in bigger injectors since they do not work as hard and can provide better control.